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Prochlorperazine overdose

Definition

Prochlorperazine overdose is poisoning from an overdose of prochlorperazine.

Alternative Names

Compazine

Poisonous Ingredient

Prochlorperazine

Where Found

Compazine

Symptoms

• Body as a whole
  • Dry mouth
  • Hypothermia (body temperature is lower than normal)
  • Incoordination
  • Fever
  • Tremor
  • Inability to completely empty the bladder
  • Weakness
  • Difficulty swallowing
  • Salivation
  • Convulsions
  • Stiff muscles in neck, face, or back
  • Alteration of menstrual patterns
  • Muscle spasms
• Eyes, ears, nose, and throat
  • Nasal congestion
  • Blurred vision
  • Photosensitivity
• Skin
  • Rash
• Gastrointestinal
  • Nausea
  • Constipation
  • Loss of appetite
• Heart and blood vessels
  • Low blood pressure (severe)
  • Rapid heartbeat
• Nervous system
  • Drowsiness
  • Coma
  • Disorientation

Home Care

Call Poison Control for instructions.

Before Calling Emergency

Determine the following information:

• The patient's age, weight, and condition
• The name of the product (ingredients and strengths if known)
• The time it was swallowed
• The amount swallowed
• If the medication was prescribed for the patient

They will instruct you if it is necessary to take the patient to the hospital. See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.

What to Expect at the Emergency Room

Some or all of the following may be performed or given:

• Gastric lavage 
• Activated charcoal
• Laxative
• Replacement of fluids
• Antidote
• Treatment of other symptoms

Outlook (Prognosis)

Recovery depends on the nature and extent of the damage done. Survival past 2 weeks is usually a good sign.

Review Date: 5/10/2005
Reviewed By: William D. Whetstone, M.D., Division of Emergency Medicine, University of California San Francisco, San Francisco, CA. Review provided by VeriMed Healthcare Network.