carbinoxamine, methscopolamine, and pseudoephedrine

Generic Name: carbinoxamine, methscopolamine, and pseudoephedrine (car bih NOX ah meen, meth skoe PALL ah meen, and soo doe eh FEH drin)
Brand Names: Pannaz, Pannaz S

What is the most important information I should know about carbinoxamine, methscopolamine, and pseudoephedrine?

Use caution when driving, operating machinery, or performing other hazardous activities. Carbinoxamine, methscopolamine, and pseudoephedrine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking carbinoxamine, methscopolamine, and pseudoephedrine.

Carbinoxamine, methscopolamine, and pseudoephedrine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any other medicine without first talking to your doctor.

Do not take more of this medication than is recommended. If your symptoms do not improve, or if they worsen, talk to your doctor.

What is carbinoxamine, methscopolamine, and pseudoephedrine?

Carbinoxamine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in the body. Carbinoxamine prevents sneezing; itchy, watery eyes and nose; and other symptoms of allergies and hay fever.

Methscopolamine is an antisecretory agent. It reduces secretions in the nose that may cause sneezing, runny nose, and postnasal drip.

Pseudoephedrine is a decongestant. It constricts (shrinks) blood vessels (veins and arteries). This reduces the blood flow and allows nasal passages to open up.

Carbinoxamine, methscopolamine, and pseudoephedrine is used to treat nasal congestion; runny nose; postnasal drip; itchy, watery eyes; and other symptoms associated with allergies, hay fever, and the common cold.

Carbinoxamine, methscopolamine, and pseudoephedrine may also be used for purposes other than those listed in this medication guide.

Who should not take carbinoxamine, methscopolamine, and pseudoephedrine?

Do not take carbinoxamine, methscopolamine, and pseudoephedrine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), or selegiline (Eldepryl) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

kidney disease;
liver disease;
diabetes;
glaucoma;
heart disease or high blood pressure;
thyroid problems;
asthma, emphysema or chronic bronchitis; or
difficulty urinating or have an enlarged prostate.

You may not be able to take carbinoxamine, methscopolamine, and pseudoephedrine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Carbinoxamine, methscopolamine, and pseudoephedrine is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Carbinoxamine, methscopolamine, and pseudoephedrine pass into breast milk and may affect a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

If you are over 65 years of age, you may be more likely to experience side effects from carbinoxamine, methscopolamine, and pseudoephedrine. Your doctor may prescribe a lower dose of the medication.

How should I take carbinoxamine, methscopolamine, and pseudoephedrine?

Take carbinoxamine, methscopolamine, and pseudoephedrine exactly as directed. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Carbinoxamine, methscopolamine, and pseudoephedrine can be taken with or without food.

Swallow the tablets with a full glass of water.

Do not crush or chew the tablets. Swallow them whole. If swallowing the tablets is difficult, they can be broken in half where scored, but should not be crushed or chewed. A liquid form of this medication is also available.

To ensure that you get a correct dose, measure the liquid form of carbinoxamine, methscopolamine, and pseudoephedrine with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Do not take more of this medication than is recommended. If your symptoms do not improve, or if they worsen, talk to your doctor.

Store carbinoxamine, methscopolamine, and pseudoephedrine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a carbinoxamine, methscopolamine, and pseudoephedrine overdose may include dry mouth, large pupils, flushing, nausea, vomiting, hyperactivity, or hallucinations.

What should I avoid while taking carbinoxamine, methscopolamine, and pseudoephedrine?

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking carbinoxamine, methscopolamine, and pseudoephedrine.

Do not take other over-the-counter cough, cold, allergy, diet, or sleep aids while taking carbinoxamine, methscopolamine, and pseudoephedrine without first talking to your doctor or pharmacist. Other medications may also contain carbinoxamine, methscopolamine, pseudoephedrine, or other similar drugs. You may accidentally take too much of these medicines.

What are the possible side effects of carbinoxamine, methscopolamine, and pseudoephedrine?

Serious side effects are unlikely to occur. Stop taking carbinoxamine, methscopolamine, and pseudoephedrine and seek emergency medical attention if you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take carbinoxamine, methscopolamine, and pseudoephedrine and talk to your doctor if you experience

dryness of the eyes, nose, or mouth;
drowsiness or dizziness;
blurred vision; or
difficulty urinating.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect carbinoxamine, methscopolamine, and pseudoephedrine?

Before taking carbinoxamine, methscopolamine, and pseudoephedrine, tell your doctor if you are taking digoxin (Lanoxin, Lanoxicaps). Methscopolamine may increase the level of digoxin in the blood.

Drugs other than those listed here may also interact with carbinoxamine, methscopolamine, and pseudoephedrine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines including vitamins, minerals, and herbal products.

Where can I get more information?

Your pharmacist has additional information about carbinoxamine, methscopolamine, and pseudoephedrine written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.