erythromycin

(er ith roe MYE sin)
E-Mycin, E.E.S. Granules, E.E.S.-200, E.E.S.-400, E.E.S.-400 Filmtab, Ery-Tab, Eryc, EryPed, Eryped 200, Eryped 400, Erythrocin Stearate Filmtab, Erythrocot, Ilosone, MY-E, PCE Dispertab, Robimycin

What is the most important information I should know about erythromycin?

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Do not take erythromycin if you are taking terfenadine (Seldane, Seldane-D), astemizole (Hismanal), cisapride (Propulsid), or pimozide (Orap). Erythromycin may interact with these medicines resulting in dangerous or life-threatening irregular heartbeats.

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Take all of the erythromycin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

What is erythromycin?

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Erythromycin is in a class of drugs called macrolide antibiotics. Erythromycin fights bacteria in the body.

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Erythromycin is used to treat many different types of bacterial infections, such as tonsillitis, bronchitis, pneumonia, whooping cough, Legionnaire's disease, chlamydia, gonorrhea, skin infections, and others.

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Erythromycin may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking erythromycin?

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Do not take erythromycin if you are taking any of the following medicines:

terfenadine (Seldane, Seldane-D);

astemizole (Hismanal);

cisapride (Propulsid); or

pimozide (Orap).

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Erythromycin may interact with these medicines resulting in dangerous or life-threatening irregular heartbeats.

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Before taking erythromycin, tell your doctor if you have liver disease. You may not be able to take erythromycin, or you may require a dosage adjustment or special monitoring during treatment.

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Erythromycin is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Erythromycin has been used quite extensively during pregnancy, and it is generally considered to be safe. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

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Erythromycin passes into breast milk but does not appear to be harmful to a nursing baby. Erythromycin is generally considered to be safe for use by breast-feeding mothers. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take erythromycin?

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Take erythromycin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

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Take each dose with a full glass (8 ounces) of water.

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Erythromycin can be taken on an empty stomach or with food or milk.

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Do not crush, chew, or break the extended-release or enteric-coated forms of erythromycin such as E-Mycin, Eryc, Ery-Tab, or Erythromycin Delayed-Release Capsules. Swallow them whole.

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Take all of the erythromycin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

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Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

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Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

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Seek emergency medical attention if an overdose is suspected.

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Symptoms of an erythromycin overdose include nausea, vomiting, diarrhea, and abdominal discomfort.

What should I avoid while taking erythromycin?

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Avoid prolonged exposure to sunlight. Erythromycin may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

What are the possible side effects of erythromycin?

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If you experience any of the following serious side effects, stop taking erythromycin and seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or

liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue).

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Other, less serious side effects may be more likely to occur. Continue to take erythromycin and talk to your doctor if you experience

nausea, vomiting, diarrhea, or abdominal pain (take erythromycin with food or milk if you experience any of these side effects);

dizziness, fatigue, or headache;

vaginal yeast infection;

a rash; or

increased sensitivity to sunlight.

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Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect erythromycin?

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Do not take erythromycin if you are taking any of the following medicines:

terfenadine (Seldane, Seldane-D);

astemizole (Hismanal);

cisapride (Propulsid); or

pimozide (Orap).

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Erythromycin may interact with these medicines resulting in dangerous or life-threatening irregular heartbeats.

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Before taking erythromycin, tell your doctor if you are taking

digoxin (Lanoxin);

disopyramide (Norpace);

warfarin (Coumadin);

theophylline (Theo-Dur, Theobid, and others);

midazolam (Versed) or triazolam (Halcion);

ergotamine (Ercaf, Cafergot, Ergostat, Ergomar) or dihydroergotamine (D.H.E. 45, Migranal);

carbamazepine (Tegretol);

phenytoin (Dilantin);

valproic acid (Depakote, Depakene);

tacrolimus (Prograf);

cyclosporine (Sandimmune, Neoral);

lovastatin (Mevacor) or simvastatin (Zocor);

bromocriptine (Parlodel); or

other antibiotics.

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You may not be able to take erythromycin, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

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Drugs other than those listed here may also interact with erythromycin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

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Your pharmacist has additional information about erythromycin written for health professionals that you may read.

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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.