papain-urea topical


(PA pain-you REE ah)
Accuzyme, Ethezyme 830, Gladase, Kovia, Panafil, Ziox


What is the most important information I should know about papain-urea topical?
Avoid getting papain-urea topical in the eyes. If this occurs, rinse the eyes thoroughly with water.
Do not use other topical preparations on the affected area unless directed to do so by your doctor.


What is papain-urea topical?
Papain is a substance from the papaya fruit. Papain breaks down certain proteins.
Urea also breaks down protein.
Papain-urea topical is used to debride (remove or breakdown) dead tissue in wounds such as bed sores, ulcers, burns, surgical wounds, cysts, carbuncles, and others.
Papain-urea topical may also be used for purposes other than those listed in this medication guide.


What should I discuss with my healthcare provider before using papain-urea topical?
Before using papain-urea topical, talk to your doctor if you have other medical conditions or allergies. You may not be able to use papain-urea topical, or you may require a dosage adjustment or special monitoring during treatment.
It is not known whether papain-urea will be harmful to an unborn baby. Do not use papain-urea topical without first talking to your doctor if you are pregnant or could become pregnant during treatment.
It is not known whether papain-urea passes into breast milk. Do not use papain-urea topical without first talking to your doctor if you are breast-feeding a baby.


How should I use papain-urea topical?
Use papain-urea topical exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Wash your hands before and after applying the medication.
Clean the wound as directed. Apply the medication directly to the wound. Cover with an appropriate dressing as directed by your healthcare provider.
Reapply the medication and change the dressing as directed.
It is important to use papain-urea regularly and for the full amount of time prescribed to get the most benefit.
Store papain-urea topical at room temperature away from moisture and heat.


What happens if I miss a dose?
Apply the missed dose as soon as you remember.


What happens if I overdose?
Seek emergency medical attention if an overdose of papain-urea is suspected or if the medication has been ingested.
Symptoms of an overdose of papain-urea topical are not known.


What should I avoid while using papain-urea topical?
Avoid getting papain-urea topical in the eyes. If this occurs, rinse the eyes thoroughly with water.
Do not use other topical preparations on the affected area unless directed to do so by your doctor.


What are the possible side effects of papain-urea topical?
If you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, face, or tongue; or hives), stop using papain-urea topical and seek emergency medical attention.
Other less serious side effects may be more likely to occur. Continue to use papain-urea topical and talk to your doctor if you experience irritation or slight burning of the affected area.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect papain-urea topical?
Do not use other topical preparations on the affected area unless directed to do so by your doctor.
Drugs other than those listed here may also interact with papain-urea topical. Talk to your doctor and pharmacist before taking or using any prescription or over the counter medicines, including vitamins, minerals, and herbal products.


Where can I get more information?
Your pharmacist has additional information about papain-urea topical written for health professionals that you may read.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version: 1.02. Revision Date: 1/23/04.