It's harmful to people that have misophonia.
Commercials don't much care for anyone beyond maximising sales. (Might replace "commercials" with "people" and "sales" with "themselves", but that's debatable.)
Personally, I would prefer commercials not to exist altogether, yet it doesn't seem to provide sufficient incentive for them to take a long walk off a short pier. So it falls to me to filter them out. Such is our mutual animosity.
The answers are subtle and take a while to explain. Get "Dress For Success" by John Molloy. You will find the answers there.
Short version: Shows and commercials operate on symbols. Everybody knows that commercials for bacon and steaks are lousy without plenty of "sizzle". That is because the sizzle is the symbol of the taste. Sound engineers have always considered clinking spoons and glassware to be the accepted symbols of dinner time. Any dinner time. And so on.